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How many COVID-19 vaccine doses do I need if I’m immunocompromised?

Last Updated: 07/18/2022

Children aged 6 months through 4 years who are moderately or severely immunocompromised should get a total of 3 doses of Pfizer or Moderna COVID-19 vaccine to stay up to date.

Children aged 5 to 11 years who are moderately or severely immunocompromised should get a total of 4 doses of Pfizer COVID-19 vaccine or 3 doses or Moderna COVID-19 vaccine to stay up to date.

  • The 4 doses of Pfizer include the primary series of 3 doses plus 1 booster (4th dose).
  • The 3 doses of Moderna include the primary series of 3 doses. Boosters are not recommended at this time for any children who have completed the Moderna COVD-19 primary series.

People aged 12 to 17 years who are moderately or severely immunocompromised should get a total of 5 doses of Pfizer or 3 doses of Moderna COVID-19 vaccine to stay up to date.

  • The 5 Pfizer doses include the primary series of 3 doses, plus two booster doses.
  • The 3 doses of Moderna include the primary series of 3 doses. Boosters are not recommended at this time for any children who have completed the Moderna COVD-19 primary series.

People aged 18 years and older who are moderately or severely immunocompromised should get a total of 5 doses of Pfizer or Moderna COVID-19 vaccine to stay up to date.

  • The 5 doses include the primary series of 3 doses, plus two booster doses.

People 18 years and older who are moderately or severely immunocompromised and received the 1-dose J&J COVID-19 vaccine should get a total of 4 doses to stay up to date.

  • The 4 doses include the 1-dose J&J vaccine, a 2nd dose of either a Pfizer or Moderna COVID-19 vaccine (mRNA COVID-19 vaccines), plus 2 mRNA COVID-19 vaccine boosters.

You must wait several weeks before receiving each additional dose. For more information, refer to the CDC's COVID-19 vaccine guidelines for immunocompromised people.

Vaccine appointments can be made at any existing vaccination location without a prescription. At this time, 5 through 17-year-olds can only receive the Pfizer vaccine.

Note: If you are immunocompromised, no proof of this status is required. Persons who have immune compromise should notify your provider when scheduling your next shot to ensure you are getting the right dose at the right time.

Who is moderately or severely immunocompromised?

Many conditions and treatments can cause a person to be immunocompromised (having a weakened immune system). According to the CDC, moderate and severe immunocompromising conditions include, but are not limited to:

  • Active cancer treatment for tumors or cancers of the blood
  • Receipt of organ transplant and are taking medicine to suppress the immune system
  • Receipt of a stem cell transplant within the last 2 years or are taking medicine to suppress the immune system
  • Moderate or severe primary immunodeficiency (such as DiGeorge syndrome and Wiskott-Aldrich syndrome)
  • Advanced or untreated HIV infection
  • Active treatment with high-dose corticosteroids or other drugs that may suppress your immune response

Source: https://www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations/immuno.html